The early maps of Pennsylvania show that the area of land now called Middletown was "A Susquehannock Indian Town" (1715). Some lodges of the Conoy or Ganawese Indians were located on the grounds in the area bounded by present day Pine, Spruce, Main, and High Streets. These two tribes were "remnants" of the once-powerful Susquehannock Nation. The Scotch-Irish were the first Caucasian settlers of this area.

 

Near the mouth of the Swatara Creek, a rough Irishman named "Anderson" claimed 423 acres on the Susquehanna River. This claim dates back at least to 1728. Jacob Job, a Philadelphia merchant, acquired the rights to the Anderson claim in 1732 Jeremiah Job, a relative of Jacob, was the first English settler of record of lands composing what is now the town. His home was a long two-story log house located on the northwest corner of Main and Pine Streets. The town was founded in 1755 and flourished due to several booming businesses from a stove works, lumber mill, flouring factory and planing mills. 

 

Middletown's history is still evident in the town today, with examples of early log cabins lining its streets, as well as buildings displaying the late Victorian and Brownstone styles. The town is home to quaint restaurants, 2nd oldest running Theatre in the country, historic rail stations and a picturesque downtown that hosts events throughout the year. Explore the original 1755 section of town,  which encompasses the area centered along Main Street Between present-day Union and Vine Streets and High and Water Streets.

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